Development of Analytical Method for Determination of Lisinopril Tablets Using Rp-hplc Method
نویسندگان
چکیده
A high performance liquid chromatographic method was developed, validated and applied for determination of lisinopril in pharmaceutical formulations. A LiChrospher RP-18 (10 μm, 250x 4 mm) column was used with a mobile phase consisting of acetonitrile: phosphate buffer (30: 70% v/v, pH 2.0), a quantitative evaluation was performed at 215 nm with flow rate of 1 mL/min, and column cooler temperature was maintained at 35 oC. The retention time was about 6 min. This method is suitable for assay of lisinopril tablets and it can be applied in routine quality control, as it is accurate, precise and simple.
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